Industrial action by ASLEF means that no Southern, Thameslink or Gatwick Express services will run.
Additionally, services will again be limited on Saturday 13 May, with trains starting later in the day and final trains expected to be much earlier.
Due to overtime bans, an amended timetable is expected across the local area from Monday 15 to Saturday 20 May.
Currently, further strike dates are planned for Wednesday 31 May and Saturday 3 June, where again there will be no trains running.
Cost of policing Crowborough migrant camp in East Sussex revealed
Piltdown Golf Club nominated for an award
Man arrested after van collides into Polegate's Harvester
Southern Water customers are set for a bill increase
East Sussex man wanted on recall to prison
Fire breaks out at Hare & Hounds Framfield
NHS eases mask wearing rules
People stranded at Birling Gap after cliff fall