The shop at Lewes House on the High Street will be open from 15 October.
The annual pop-up shop will be run by volunteers until 17 December, with a wide range of cards and gifts - all raising money for local and national charities.
The charity aims to raise a total of £500,000 across the country this Christmas, to support more than 70 charities
Cars for Good Causes is a charity which has operated for more than 60 years. Supported charities include Diabetes UK, RNLI, British Heart Foundation, Alzheimers UK, Epilepsy UK, MS Society and a host of local charities.
The Shop Manager at Lewes ays: "We can't wait to meet everyone this year in our shop! Please come volunteer with us, or come and get your Christmas gifts whilst supporting the charities of your choice. I wish everyone a very festive Christmas and hope to see you soon!"
Find more details about the charity and a list of all stores on their website.
Day Surgery at Uckfield Hospital to remain closed
Former Eastbourne Pub to become a vets
Plans approved to turn Original Factory Shop in Heathfield into a gym
Funding open to boost physical activity and health in Wealden
Crackdown on drink & drug drivers in East Sussex
Sussex Police discover cannabis factory in Eastbourne
Hailsham Christmas Market to Take Place on Saturday 13 December
Patients welcomed into Five Ashes hospice as it re-opens its doors
